HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dipropan-2-yl(4-aminophenyl)phosphonate → 3-(5,5-Dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dipropan-2-yl(4-aminophenyl)phosphonate | HCID 86653993 | — |
| Reactant | 5,5-Dimethyl-2-(3-nitrophenyl)-1,3,2-dioxaphosphinane 2-oxide | HCID 86653996 | — |
| Product | 3-(5,5-Dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)aniline | HCID 86653995 | 63% |
Reaction Steps
Prepared according to the procedure described for dipropan-2-yl(4-aminophenyl)phosphonate using 5,5-dimethyl-2-(3-nitrophenyl)-1,3,2-dioxaphosphinane 2-oxide. Yield: 63%. 1H-NMR (DMSO-d6, 400 MHz): δ=0.94 (s, 3H), 1.07 (s, 3H), 3.84 (dd, J=9.6, 10.8 Hz, 2H), 4.07 (dd, J=11.2, 14.0 Hz, 2H), 5.43 (s, br, 2H), 6.75-6.78 (m, 2H), 6.88 (d, 1H), 7.16 (m, 1H). MS: m/z 242.11 [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399433B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-086e14b819a54ca296b6e2b643c777ac |
| Source note | uspto-grants-2013_03 |