HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Chloromethyl)-2-fluoro-5-methoxy-4-nitrobenzene → 5-(Chloromethyl)-1-fluoro-3-methoxy-2-nitrobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Chloromethyl)-2-fluoro-5-methoxy-4-nitrobenzene | HCID 67255107 | — |
| Reactant | (3-Fluoro-5-methoxy-4-nitrophenyl)methanol | HCID 67256643 | — |
| Product | 5-(Chloromethyl)-1-fluoro-3-methoxy-2-nitrobenzene | HCID 67254475 | — |
Reaction Steps
The title compound was prepared using the procedure from Compound 130C (1-(chloromethyl)-2-fluoro-5-methoxy-4-nitrobenzene) with (3-fluoro-5-methoxy-4-nitrophenyl)methanol (Compound 146D). 1H NMR (CDCl3, 400 MHz): δ=3.96 (s, 3H), 4.55 (s, 2H), 6.87-6.90 (m, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399433B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-1d7213f84c0b4ea3aee169106deb77c9 |
| Source note | uspto-grants-2013_03 |