HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoro-6-nitroanisole → 3-Fluoro-2-methoxyaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoro-6-nitroanisole | HCID 598606 | — |
| Reactant | 2-Amino-5-fluoro-N-methylbenzamide | HCID 43132558 | — |
| Product | 3-Fluoro-2-methoxyaniline | HCID 581109 | — |
Reaction Steps
The title compound was prepared according to the procedure for Compound 102A (2-Amino-5-fluoro-N-methylbenzamide) with 1-fluoro-2-methoxy-3-nitrobenzene (Compound 147J). 1H NMR (CDCl3, 400 MHz): δ=3.92 (d, J=1.52 Hz, 3H), 6.44-6.53 (m, 2H), 6.80 (td, J=8.15, 5.68 Hz, 1H). MS (ES+): m/z 142.07 [MH+] (TOF, polar).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399433B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-ba09b96f7e364f13b399b7fa247a9788 |
| Source note | uspto-grants-2013_03 |