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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1947977Generated: November 2, 2026

(2-Aminophenyl)(4-methylpiperazin-1-yl)methanone → HCID 58293069, compound

https://huagongshe.com/reaction/1947977

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Aminophenyl)(4-methylpiperazin-1-yl)methanoneHCID 550840—
ReactantDiethyl (4-{[4-chloro-5-(trifluoromethyl)pyrimidin-2-yl]amino}benzyl)phosphonateHCID 86654003—
ProductHCID 58293069HCID 58293069—

Reaction Steps

The title product was prepared according to the procedure for Example 102 using diethyl(4-{[4-chloro-5-(trifluoromethyl)pyrimidin-2-yl]amino}benzyl)phosphonate and the commercially available (2-aminophenyl)-(4-methylpiperazin-1-yl)methanone. MS (ES+): m/z 607.37 (100) [MH+]; HPLC: tR=0.66 min (UPLC, purity).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399433B2
Source datasetuspto-grants-2013_03
ORD IDord-4bb9b2dbd35247f5b80b958616af8f7c
Source noteuspto-grants-2013_03