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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1948015Generated: October 31, 2026

7-Amino-4-methoxy-2-methyl-2,3-dihydroisoindol-1-one → 7-Amino-2-methyl-4-(propan-2-yloxy)-2,3-dihydro-1H-isoindol-1-one

https://huagongshe.com/reaction/1948015

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Amino-4-methoxy-2-methyl-2,3-dihydroisoindol-1-oneHCID 67253941—
Reactant2-Methyl-7-nitro-4-(propan-2-yloxy)-2,3-dihydro-1H-isoindol-1-oneHCID 67254762—
Product7-Amino-2-methyl-4-(propan-2-yloxy)-2,3-dihydro-1H-isoindol-1-oneHCID 67255864—

Reaction Steps

The title compound was prepare according to the procedure for 7-Amino-4-methoxy-2-methyl-2,3-dihydro-1H-isoindol-1-one (Compound 205A) using 2-Methyl-7-nitro-4-(propan-2-yloxy)-2,3-dihydro-1H-isoindol-1-one (Compound 207B). MS (ES+): m/z 222.21 (100) [MH+]; HPLC: tR=0.93 min (UPLC, analytical).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399433B2
Source datasetuspto-grants-2013_03
ORD IDord-4dece53e18384c15b2f3addff86a4efe
Source noteuspto-grants-2013_03