(4-Methoxyphenyl)boronic acid → HCID 58966926, compound

Participants

Reaction Steps

According to Scheme 13 Method C: The title compound was prepared from 1-(3-fluorobenzyl)-1,2-dihydro-2-oxopyridin-4-yl trifluoromethanesulfonate (1 eq, 0.28 mmol, 0.10 g) and 4-methoxyphenyl boronic acid (1.5 eq, 0.43 mmol, 65 mg) according to the procedure described for Example 1 Step 3. The crude product was purified by flash chromatography on silica gel using cyclohexane/AcOEt 70/30 as eluent to afford the title compound (0.17 mmol, 52 mg, 59%) was obtained as a white solid.

Provenance & Evidence