Methanol → 5-Methoxy-1-(4-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinoline
Reaction equation
[BH4-:25].[CH3:1][O:2][c:3]1[c:4]2[c:9]([cH:10][cH:11][cH:12]1)[C:8]([c:13]1[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]1)=[N:7][CH2:6][CH2:5]2.[CH3:23][OH:24].[Na+:26].[OH2:27]>>[CH3:1][O:2][c:3]1[c:4]2[c:9]([cH:10][cH:11][cH:12]1)[CH:8]([c:13]1[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]1)[NH:7][CH2:6][CH2:5]2Participants
6
Sources & evidence
- ORD record
- ord-1ae9c306dc9149e18a4b06003030fde8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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