Benzoyl chloride → HCID 87497032, compound

Participants

Reaction Steps

After dissolving 2-hydroxyimino-2-phenylacetonitrile (1.0 g, 6.84 mmol) in CH2Cl2 (30 ml), benzoylchloride (1.02 ml, 8.89 mmol) was slowly added at 0° C. under the presence of triethylamine (1.24 ml, 8.89 mmol). After stirring reaction solution for 1 hour, the reaction was quenched by 1 N hydrochloric acid and the reaction solution was extracted with dichloromethane. A pure compound of (E)-1-cyano-benzaldehyde O-benzoyloxime (14) (1.30 g, 81%) was obtained by separating the residue with silica gel column chromatography.

Provenance & Evidence