3,4-Dichloroaniline → HCID 67505254, compound

HRID 1948842Notes

Reaction equation

HRID 1948842 reaction equation
NC1C(C)=CC=CC=1[C:9]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[F:17])=[O:10].[Cl:18][C:19]1[CH:20]=[C:21]([CH:23]=[CH:24][C:25]=1[Cl:26])[NH2:22].FC1C=CC=CC=1C#N>>[NH2:22][C:21]1[CH:20]=[C:19]([Cl:18])[C:25]([Cl:26])=[CH:24][C:23]=1[C:9]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[F:17])=[O:10]

Participants

4

Reactant 3

HCID 72573,4-DichloroanilineHCID 678552-FluorobenzonitrileHCID 21701284HCID 21701284, compound

Product 1

HCID 67505254HCID 67505254, compoundYield 17%

Procedure

In a manner similar to that described above for compound 1b, 3,4-dichloroaniline and 2-fluorobenzonitrile were converted to 1ad (17% yield) MS m/z=284 (M+H).

Sources & evidence

ORD record
ord-64de2548465a4f9a8c9f82948792118e
Source dataset
uspto-grants-2013_03
Patent number
US08399659B2

Reaction notes

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