HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluidine → (2-Amino-5-methyl-phenyl)-(2,6-difluoro-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluidine | HCID 7813 | — |
| Reactant | 2,6-Difluorobenzoyl chloride | HCID 87438 | — |
| Reactant | 4-Chloro-2-(4-fluorobenzoyl)aniline | HCID 10955955 | — |
| Product | (2-Amino-5-methyl-phenyl)-(2,6-difluoro-phenyl)-methanone | HCID 67505674 | 16% |
Reaction Steps
In a manner similar to that described above for compound 1t, p-toluidine and 2,6-difluorobenzoyl chloride were converted to 1aj (16% yield) MS m/z=248 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399659B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-7b75403f0fbf41e8b75fc17ba23a590b |
| Source note | uspto-grants-2013_03 |