HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Difluorobenzoyl chloride → (2-Amino-5-chloro-phenyl)-(2,3-difluoro-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Difluorobenzoyl chloride | HCID 519549 | — |
| Reactant | tert-butyl N-(4-chlorophenyl)carbamate | HCID 546372 | — |
| Product | (2-Amino-5-chloro-phenyl)-(2,3-difluoro-phenyl)-methanone | HCID 67505670 | 14% |
Reaction Steps
In a manner similar to that described above for compound 1aa, 4-Chloro-N-Boc-aniline and 2,3-difluoro-benzoyl chloride were converted to 1v (14% yield) MS m/z=268 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399659B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-df580ca8ad60492a99ca4f1c20dc9fe1 |
| Source note | uspto-grants-2013_03 |