3-Chloro-2-hydrazinylpyridine → HCID 53235559, compound

HRID 1948985Notes

Reaction equation

HRID 1948985 reaction equation
[C:1]([O:4][CH2:5][C:6](OC)=[CH:7][C:8](=[O:13])[C:9]([Cl:12])([Cl:11])[Cl:10])(=[O:3])[CH3:2].[Cl:16][C:17]1[C:18]([NH:23][NH2:24])=[N:19][CH:20]=[CH:21][CH:22]=1>C(O)C>[C:1]([O:4][CH2:5][C:6]1[CH2:7][C:8]([OH:13])([C:9]([Cl:10])([Cl:11])[Cl:12])[N:23]([C:18]2[C:17]([Cl:16])=[CH:22][CH:21]=[CH:20][N:19]=2)[N:24]=1)(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 5561003-Chloro-2-hydrazinylpyridineHCID 75985013HCID 75985013, compound

Product 1

HCID 53235559HCID 53235559, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
25 °C

Procedure

27.5 g (0.1 mol) of 5,5,5-trichloro-2-methoxy-4-oxopent-2-en-1-yl acetate and 14.4 g (0.1 mol) of 3-chloro-2-hydrazinopyridine were initially charged in 200 ml of ethanol, and the mixture was stirred at 25° C. for 3 h. The precipitate was filtered off and washed with cyclohexane.

Workup

  1. filtrationThe precipitate was filtered off
  2. washwashed with cyclohexane

Sources & evidence

ORD record
ord-79d913436521401a8c4fddba5dee619a
Source dataset
uspto-grants-2013_03
Patent number
US08399679B2

Reaction notes

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