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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1948992Generated: October 30, 2026

HCID 68576099, compound → HCID 68574310, compound

https://huagongshe.com/reaction/1948992

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68576099HCID 68576099—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 68574310HCID 68574310—

Reaction Steps

(2-Methoxy-benzyl)-[6-((E)-2-pyridin-4-yl-vinyl)-quinolin-2-yl]-amine (example 2, 51 mg, 0.139 mmol) was dissolved in 20 mL ethanol. Palladium on charcoal (10%, 15 mg, 0.014 mmol) was added and the reaction mixture war hydrogenated with a hydrogen balloon overnight. The palladium was filtered off and the solvent was evaporated. The title compound was obtained as a yellow oil (40 mg, 78%), MS: m/e=370.1 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399674B2
Source datasetuspto-grants-2013_03
ORD IDord-a3b8e2446e024db0bce0f68ba516d779
Source noteuspto-grants-2013_03