2-Methoxybenzylamine → HCID 25235530, compound

HRID 1949008Notes

Reaction equation

HRID 1949008 reaction equation
Cl[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7](Cl)[CH:8]=2)[N:3]=1.[CH3:13][O:14][C:15]1[CH:22]=[CH:21][CH:20]=[CH:19][C:16]=1[CH2:17][NH2:18].[F:23][C:24]([F:35])([F:34])[O:25][C:26]1[CH:33]=[CH:32][CH:31]=[CH:30][C:27]=1[CH2:28][NH2:29]>>[CH3:13][O:14][C:15]1[CH:22]=[CH:21][CH:20]=[CH:19][C:16]=1[CH2:17][NH:18][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([NH:29][CH2:28][C:27]3[CH:30]=[CH:31][CH:32]=[CH:33][C:26]=3[O:25][C:24]([F:23])([F:34])[F:35])[CH:8]=2)[N:3]=1

Participants

4

Reactant 3

HCID 812922-MethoxybenzylamineHCID 6075022,6-DichloroquinolineHCID 2777251(2-(Trifluoromethoxy)phenyl)methanamine

Product 1

HCID 25235530HCID 25235530, compound

Procedure

The title compound, MS: m/e=454.0 (M+H+), was prepared in accordance with the general method of example 1 from 2,6-dichloroquinoline, 2-methoxybenzylamine and 2-(trifluoromethoxy)benzylamine.

Sources & evidence

ORD record
ord-e7efece0ff3345789dcf9107f34fa279
Source dataset
uspto-grants-2013_03
Patent number
US08399674B2

Reaction notes

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