2-Methoxybenzylamine → HCID 68574371, compound

HRID 1949035Notes

Reaction equation

HRID 1949035 reaction equation
C([NH:4][C:5]1[C:14]2[C:9](=[CH:10][CH:11]=[C:12](Cl)[CH:13]=2)[N:8]=[C:7]([NH:16][CH2:17][C:18]2[CH:23]=[CH:22][C:21]([F:24])=[CH:20][C:19]=2[O:25][CH3:26])[CH:6]=1)C=C.[CH3:27][O:28][C:29]1[CH:36]=[CH:35][CH:34]=[CH:33][C:30]=1[CH2:31][NH2:32]>>[F:24][C:21]1[CH:22]=[CH:23][C:18]([CH2:17][NH:16][C:7]2[CH:6]=[C:5]([NH2:4])[C:14]3[C:9](=[CH:10][CH:11]=[C:12]([NH:32][CH2:31][C:30]4[CH:33]=[CH:34][CH:35]=[CH:36][C:29]=4[O:28][CH3:27])[CH:13]=3)[N:8]=2)=[C:19]([O:25][CH3:26])[CH:20]=1

Participants

3

Reactant 2

HCID 812922-MethoxybenzylamineHCID 68574349HCID 68574349, compound

Product 1

HCID 68574371HCID 68574371, compound

Procedure

The title compound, MS: m/e=433.2 (M+H+), was prepared in accordance with the general method of example 44 from N4-allyl-6-chloro-N2-(4-fluoro-2-methoxy-benzyl)-quinoline-2,4-diamine and 2-methoxybenzylamine

Sources & evidence

ORD record
ord-c0b4451628d640e49eae9f8cf8ba2fe8
Source dataset
uspto-grants-2013_03
Patent number
US08399674B2

Reaction notes

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