3-(Trifluoromethyl)aniline → HCID 68574802, compound

HRID 1949050Notes

Reaction equation

HRID 1949050 reaction equation
Cl[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7](Cl)[CH:8]=2)[N:3]=1.[F:13][C:14]1[CH:15]=[C:16]([CH:19]=[CH:20][CH:21]=1)[CH2:17][NH2:18].[NH2:22][C:23]1[CH:24]=[C:25]([C:29]([F:32])([F:31])[F:30])[CH:26]=[CH:27][CH:28]=1>>[F:13][C:14]1[CH:15]=[C:16]([CH:19]=[CH:20][CH:21]=1)[CH2:17][NH:18][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([NH:22][C:23]3[CH:28]=[CH:27][CH:26]=[C:25]([C:29]([F:30])([F:31])[F:32])[CH:24]=3)[CH:8]=2)[N:3]=1

Participants

4

Reactant 3

HCID 73753-(Trifluoromethyl)anilineHCID 668533-FluorobenzylamineHCID 6075022,6-Dichloroquinoline

Product 1

HCID 68574802HCID 68574802, compound

Procedure

The title compound, MS: m/e=412.3 (M+H+), was prepared in accordance with the general method of example 1 from 2,6-dichloroquinoline, 3-fluorobenzylamine and 3-aminobenzotrifluoride.

Sources & evidence

ORD record
ord-9119b521b11a4cb8b66b8be2544a7a61
Source dataset
uspto-grants-2013_03
Patent number
US08399674B2

Reaction notes

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