2,6-Dichloroquinoline → HCID 68575976, compound
Reaction equation
Cl[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7](Cl)[CH:8]=2)[N:3]=1.[CH3:13][C:14]1[O:18][C:17]([CH2:19][NH2:20])=[CH:16][CH:15]=1.[F:21][C:22]([F:33])([F:32])[O:23][C:24]1[CH:31]=[CH:30][CH:29]=[CH:28][C:25]=1[CH2:26][NH2:27]>>[CH3:13][C:14]1[O:18][C:17]([CH2:19][NH:20][C:2]2[CH:11]=[CH:10][C:9]3[C:4](=[CH:5][CH:6]=[C:7]([NH:27][CH2:26][C:25]4[CH:28]=[CH:29][CH:30]=[CH:31][C:24]=4[O:23][C:22]([F:21])([F:32])[F:33])[CH:8]=3)[N:3]=2)=[CH:16][CH:15]=1Participants
4
Procedure
The title compound, MS: m/e=428.1 (M+H+), was prepared in accordance with the general method of example 1 from 2,6-dichloroquinoline, 5-methyl-2-furanmethanamine and 2-(trifluoromethoxy)benzylamine.
Sources & evidence
- ORD record
- ord-629275ddfd5f47e2b03bf61030e38cb3
- Source dataset
- uspto-grants-2013_03
- Patent number
- US08399674B2
Reaction notes
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