3-Pyridinemethanamine → HCID 25235664, compound

HRID 1949056Notes

Reaction equation

HRID 1949056 reaction equation
C([NH:4][C:5]1[C:14]2[C:9](=[CH:10][CH:11]=[C:12](Cl)[CH:13]=2)[N:8]=[C:7]([NH:16][CH2:17][C:18]2[CH:23]=[C:22]([F:24])[CH:21]=[CH:20][C:19]=2[O:25][CH3:26])[CH:6]=1)C=C.[N:27]1[CH:32]=[CH:31][CH:30]=[C:29]([CH2:33][NH2:34])[CH:28]=1>>[F:24][C:22]1[CH:21]=[CH:20][C:19]([O:25][CH3:26])=[C:18]([CH:23]=1)[CH2:17][NH:16][C:7]1[CH:6]=[C:5]([NH2:4])[C:14]2[C:9](=[CH:10][CH:11]=[C:12]([NH:34][CH2:33][C:29]3[CH:28]=[N:27][CH:32]=[CH:31][CH:30]=3)[CH:13]=2)[N:8]=1

Participants

3

Procedure

The title compound, MS: m/e=404.5 (M+H+), was prepared in accordance with the general method of example 44 from N4-allyl-6-chloro-N2-(5-fluoro-2-methoxy-benzyl)-quinoline-2,4-diamine and 3-picolylamine

Sources & evidence

ORD record
ord-75c90b21a11b4e279870057f3e4e4911
Source dataset
uspto-grants-2013_03
Patent number
US08399674B2

Reaction notes

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