3-(Trifluoromethyl)aniline → HCID 68574398, compound
Reaction equation
Cl[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7](Cl)[CH:8]=2)[N:3]=1.[CH3:13][C:14]1[O:18][C:17]([CH2:19][NH2:20])=[CH:16][CH:15]=1.[F:21][C:22]([F:31])([F:30])[C:23]1[CH:24]=[C:25]([CH:27]=[CH:28][CH:29]=1)[NH2:26]>>[CH3:13][C:14]1[O:18][C:17]([CH2:19][NH:20][C:2]2[CH:11]=[CH:10][C:9]3[C:4](=[CH:5][CH:6]=[C:7]([NH:26][C:25]4[CH:27]=[CH:28][CH:29]=[C:23]([C:22]([F:21])([F:30])[F:31])[CH:24]=4)[CH:8]=3)[N:3]=2)=[CH:16][CH:15]=1Participants
4
Procedure
The title compound, MS: m/e=398.3 (M+H+), was prepared in accordance with the general method of example 1 from 2,6-dichloroquinoline, 5-methyl-2-furanmethanamine and 3-(trifluoromethyl)aniline.
Sources & evidence
- ORD record
- ord-d2ef94b40dab47d1b727fdf9e67c0561
- Source dataset
- uspto-grants-2013_03
- Patent number
- US08399674B2
Reaction notes
Loading…