4-Fluoroaniline → HCID 68574378, compound

HRID 1949059Notes

Reaction equation

HRID 1949059 reaction equation
Cl[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7](Cl)[CH:8]=2)[N:3]=1.[CH3:13][C:14]1[O:18][C:17]([CH2:19][NH2:20])=[CH:16][CH:15]=1.[F:21][C:22]1[CH:28]=[CH:27][C:25]([NH2:26])=[CH:24][CH:23]=1>>[F:21][C:22]1[CH:28]=[CH:27][C:25]([NH:26][C:7]2[CH:8]=[C:9]3[C:4](=[CH:5][CH:6]=2)[N:3]=[C:2]([NH:20][CH2:19][C:17]2[O:18][C:14]([CH3:13])=[CH:15][CH:16]=2)[CH:11]=[CH:10]3)=[CH:24][CH:23]=1

Participants

4

Reactant 3

HCID 97314-FluoroanilineHCID 6075022,6-DichloroquinolineHCID 27246835-Methyl-2-furylmethylamine

Product 1

HCID 68574378HCID 68574378, compound

Procedure

The title compound, MS: m/e=348.3 (M+H+), was prepared in accordance with the general method of example 1 from 2,6-dichloroquinoline, 5-methyl-2-furanmethanamine and 4-fluoroaniline.

Sources & evidence

ORD record
ord-2af693ec4eae4d3c8528e27dd12401a3
Source dataset
uspto-grants-2013_03
Patent number
US08399674B2

Reaction notes

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