Indole → HCID 59238955, compound

Participants

Reaction Steps

The title compound was prepared in a manner analogous to Example 28 except the starting indole is 5,7-diBOC-2,10-dichloro-6-hydroxyindolo[2,3-b]carbazole and the reagent is (S)-(+)-1-(tert-butoxycarbonyl)-2-pyrrolidinemethanol. 1H-NMR (400 MHz, CD3OD) δ ppm 8.44 (s, 1 H), 8.11 (d, J=2.0 Hz, 2 H), 7.41 (d, J=8.4 Hz, 2 H), 7.29 (dd, J=8.4, 2.4 Hz, 2 H), 4.36 (t, J=7.2 Hz, 2 H), 3.09-3.01 (m, 2 H), 2.62 (td, J=12.4, 2.4 Hz, 2 H), 1.96-1.87 (m, 2 H), 1.83-1.70 (m, 3 H), 1.33-1.18 (m, 2 H); MS (ESI) m/z 450.2 (M−H)−; MS (ESI) m/z 452.1 (M+H)+

Provenance & Evidence