Indole → HCID 59238986, compound

Participants

Reaction Steps

The title compound was prepared in a manner analogous to Example 28 except the starting indole is 5,7-diBOC-2,10-dichloro-6-hydroxyindolo[2,3-b]carbazole and the reagent is tert-butyl 1-(3-hydroxypropyl)piperidin-4-ylcarbamate. 1H-NMR (400 MHz, CDCl3) δ ppm 9.70 (s, 2 H), 8.33 (s, 1 H), 8.07 (d, J=2.0 Hz, 2 H), 7.43 (d, J=8.4 Hz, 2 H), 7.33 (dd, J=8.6, 2.2 Hz, 2 H), 4.33 (t, J=5.4 Hz, 2H), 3.24-3.13 (m, 2 H), 3.03-2.89 (m, 1 H), 2.84 (t, J=6.0 Hz, 2 H), 2.30-2.16 (m, 2 H), 2.15-2.06 (m, 2H), 2.04-1.93 (m, 2 H), 1.78-1.65 (m, 2 H); MS (ESI) m/z 479.1 (M−H)−; MS (ESI) m/z 481.0 (M+H)+

Provenance & Evidence