HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indole → HCID 59238888, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indole | HCID 798 | — |
| Reactant | [1-(2-Hydroxy-ethyl)-piperidin-4-yl]-carbamic acid tert-butyl ester | HCID 45076484 | — |
| Reactant | HCID 67211699 | HCID 67211699 | — |
| Product | HCID 59238888 | HCID 59238888 | — |
Reaction Steps
The title compound was prepared in a manner analogous to Example 28 except the starting indole is 5,7-diBOC-2,10-dichloro-6-hydroxyindolo[2,3-b]carbazole and the reagent is tert-butyl 1-(2-hydroxyethyl)piperidin-4-ylcarbamate. 1H-NMR (400 MHz, CDCl3) δ ppm 9.92 (s, 2 H), 8.37 (s, 1 H), 8.08 (d, J=1.6 Hz, 2 H), 7.41-7.30 (m, 4 H), 4.39 (t, J=4.6 Hz, 2 H), 3.21-3.11 (m, 2 H), 2.98-2.85 (m, 1 H), 2.75 (t, J=4.6 Hz, 2 H), 2.37-2.25 (m, 2 H), 2.06-1.96 (m, 2 H), 1.78-1.65 (m, 2 H); MS (ESI) m/z 465.1 (M−H)−; MS (ESI) m/z 467.1 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399502B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-22cb0f112b384a3f8cb35be796cab321 |
| Source note | uspto-grants-2013_03 |