Indole → HCID 59239026, compound

Participants

Reaction Steps

The title compound was prepared in a manner analogous to Example 28 except the starting indole is 5,7-diBOC-2,10-dichloro-6-hydroxyindolo[2,3-b]carbazole and the reagent is (S)-tert-butyl 1-(2-hydroxyethyl)pyrrolidin-3-ylcarbamate. 1H-NMR (400 MHz, CDCl3) δ ppm 9.91 (s, 2 H), 8.37 (s, 1H), 8.08 (d, J=1.6 Hz, 2 H), 7.40-7.29 (m, 4 H), 4.43-4.33 (m, 2 H), 3.88-3.78 (m, 1 H), 3.09-2.96 (m, 2H), 2.95-2.74 (3 H), 2.61 (dd, J=9.6, 5.0 Hz, 1 H), 2.43-2.31 (m, 1 H), 1.79-1.68 (m, 1 H); MS (ESI) m/z 451.1 (M−H)−; MS (ESI) m/z 453.0 (M+H)+

Provenance & Evidence