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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1949182Generated: October 25, 2026

Benzyloxy-acetic acid 5-chloro-2-(2,4-dichloro-phenoxy)-phenyl ester → Hydroxy-acetic acid 5-chloro-2-(2,4-dichloro-phenoxy)-phenyl ester

https://huagongshe.com/reaction/1949182

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyloxy-acetic acid 5-chloro-2-(2,4-dichloro-phenoxy)-phenyl esterHCID 57667396—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHydroxy-acetic acid 5-chloro-2-(2,4-dichloro-phenoxy)-phenyl esterHCID 57667367—

Reaction Steps

Benzyloxy-acetic acid 5-chloro-2-(2,4-dichloro-phenoxy)-phenyl ester 4 (5 grams) was dissolved in methanol (50 mL) in a pressure vessel, palladium on carbon (5%, 5 grams) was added and the mixture was stirred under an atmosphere of hydrogen (4 Kg) for 4 hours. The catalyst was removed by filtration and the methanol was distilled off to yield crude 5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399696B2
Source datasetuspto-grants-2013_03
ORD IDord-4f4f3a0d9d984f948607120e0e0cefd4
Source noteuspto-grants-2013_03