4-Fluorophenylhydrazine hydrochloride → HCID 58277448, compound

HRID 1949213Notes

Reaction equation

HRID 1949213 reaction equation
Cl.FC1C=CC(NN)=CC=1.Cl[C:12]1[CH:13]=[C:14]([N:19]2[C:23]([C:24]3[CH:29]=[C:28]([F:30])[CH:27]=[C:26](Cl)[CH:25]=3)=[CH:22][C:21]([C:32]([O:34][CH2:35][CH3:36])=[O:33])=[N:20]2)[CH:15]=[CH:16][C:17]=1[F:18]>>[F:30][C:28]1[CH:29]=[C:24]([C:23]2[N:19]([C:14]3[CH:13]=[CH:12][C:17]([F:18])=[CH:16][CH:15]=3)[N:20]=[C:21]([C:32]([O:34][CH2:35][CH3:36])=[O:33])[CH:22]=2)[CH:25]=[CH:26][CH:27]=1

Participants

3

Reactant 2

HCID 699814-Fluorophenylhydrazine hydrochlorideHCID 58277311HCID 58277311, compound

Product 1

HCID 58277448HCID 58277448, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 8A and 4-fluorophenylhydrazine hydrochloride in analogy to the synthesis of the compound of Example 21A. 23.0 g (44% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-e86596a92b074de8bdb82165ec641f0e
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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