3-Bromophenylhydrazine hydrochloride → HCID 58277385, compound

HRID 1949215Notes

Reaction equation

HRID 1949215 reaction equation
Cl.[Br:2][C:3]1[CH:4]=[C:5]([NH:9][NH2:10])[CH:6]=[CH:7][CH:8]=1.ClC1C=C(N2[C:23]([C:24]3[CH:29]=[C:28](F)[CH:27]=[C:26]([Cl:31])[CH:25]=3)=[CH:22][C:21]([C:32]([O:34][CH2:35][CH3:36])=[O:33])=N2)C=CC=1F>>[Br:2][C:3]1[CH:4]=[C:5]([N:9]2[C:23]([C:24]3[CH:29]=[CH:28][CH:27]=[C:26]([Cl:31])[CH:25]=3)=[CH:22][C:21]([C:32]([O:34][CH2:35][CH3:36])=[O:33])=[N:10]2)[CH:6]=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 337573-Bromophenylhydrazine hydrochlorideHCID 58277311HCID 58277311, compound

Product 1

HCID 58277385HCID 58277385, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 3A and 3-bromophenylhydrazine hydrochloride in analogy to the synthesis of the compound of Example 21A. 2.50 g of the title compound with 70% purity (67% of theory) are obtained.

Sources & evidence

ORD record
ord-a0f9b5799dc14c90baaf4eea399ca48d
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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