m-Chlorophenylhydrazine hydrochloride → HCID 58277402, compound

HRID 1949216Notes

Reaction equation

HRID 1949216 reaction equation
[F:1][C:2]([F:24])([F:23])[C:3]1[CH:4]=[C:5]([C:13]([O-])=[CH:14][C:15](=O)[C:16]([O:18][CH2:19][CH3:20])=[O:17])[CH:6]=[C:7]([C:9]([F:12])([F:11])[F:10])[CH:8]=1.[Li+].Cl.[Cl:27][C:28]1[CH:29]=[C:30]([NH:34][NH2:35])[CH:31]=[CH:32][CH:33]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(OCC)=O)=N2)C=CC=1F>>[F:10][C:9]([F:11])([F:12])[C:7]1[CH:6]=[C:5]([C:13]2[N:34]([C:30]3[CH:31]=[CH:32][CH:33]=[C:28]([Cl:27])[CH:29]=3)[N:35]=[C:15]([C:16]([O:18][CH2:19][CH3:20])=[O:17])[CH:14]=2)[CH:4]=[C:3]([C:2]([F:1])([F:24])[F:23])[CH:8]=1

Participants

4

Reactant 3

HCID 75331m-Chlorophenylhydrazine hydrochlorideHCID 58277311HCID 58277311, compoundHCID 76738962HCID 76738962, compound

Product 1

HCID 58277402HCID 58277402, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 19A and 3-chlorophenylhydrazine hydrochloride in analogy to the synthesis of the compound of Example 21A. 2.42 g (62% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-5f02309423904260822fa013901507f2
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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