Hydrazine, (4-chlorophenyl)-, hydrochloride (1:1) → HCID 58277374, compound

HRID 1949217Notes

Reaction equation

HRID 1949217 reaction equation
Cl.[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][NH2:10])=[CH:5][CH:4]=1.ClC1C=C(N2[C:23]([C:24]3[CH:29]=[C:28]([F:30])[CH:27]=[C:26](Cl)[CH:25]=3)=[CH:22][C:21]([C:32]([O:34][CH2:35][CH3:36])=[O:33])=N2)C=CC=1F>>[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([N:9]2[C:23]([C:24]3[CH:25]=[CH:26][CH:27]=[C:28]([F:30])[CH:29]=3)=[CH:22][C:21]([C:32]([O:34][CH2:35][CH3:36])=[O:33])=[N:10]2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 71600Hydrazine, (4-chlorophenyl)-, hydrochloride (1:1)HCID 58277311HCID 58277311, compound

Product 1

HCID 58277374HCID 58277374, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 8A and 4-chlorophenylhydrazine hydrochloride in analogy to the synthesis of the compound of Example 21A. 43.4 g (87% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-ef9bbaf1069e41c79448ebc310bc8605
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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