3-Hydrazinylbenzonitrile--hydrogen chloride (1/1) → HCID 58277372, compound

HRID 1949222Notes

Reaction equation

HRID 1949222 reaction equation
Cl.[C:2]([C:4]1[CH:5]=[C:6]([NH:10][NH2:11])[CH:7]=[CH:8][CH:9]=1)#[N:3].ClC1C=C(N2[C:24]([C:25]3[CH:30]=[C:29]([F:31])[CH:28]=[C:27]([Cl:32])[CH:26]=3)=[CH:23][C:22]([C:33]([O:35][CH2:36][CH3:37])=[O:34])=N2)C=CC=1F>>[Cl:32][C:27]1[CH:26]=[C:25]([C:24]2[N:10]([C:6]3[CH:7]=[CH:8][CH:9]=[C:4]([C:2]#[N:3])[CH:5]=3)[N:11]=[C:22]([C:33]([O:35][CH2:36][CH3:37])=[O:34])[CH:23]=2)[CH:30]=[C:29]([F:31])[CH:28]=1

Participants

3

Reactant 2

HCID 164953403-Hydrazinylbenzonitrile--hydrogen chloride (1/1)HCID 58277311HCID 58277311, compound

Product 1

HCID 58277372HCID 58277372, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 1A and 3-cyanophenylhydrazine hydrochloride in analogy to the synthesis of the compound of Example 21A. 1.96 g of the title compound with 55% purity (86% of theory) are obtained.

Sources & evidence

ORD record
ord-05b29c1e0db24e25b42f8e85d2e54a98
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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