HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → HCID 58277284, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | HCID 58277401 | HCID 58277401 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 58277284 | HCID 58277284 | 40.3% |
Reaction Steps
41.5 mg (0.10 mmol) of the compound of Example 68A and 83 μl (0.99 mmol) of pyrrolidine in 3 ml of ethanol are stirred at 80° C. overnight. The reaction mixture is subsequently purified by preparative HPLC (RP18 column; mobile phase: acetonitrile/water gradient). 18.3 mg of the title compound are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399682B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-1f1135e03249432a89cb097bbd6b5596 |
| Source note | uspto-grants-2013_03 |