HCID 58277326, compound → HCID 58277390, compound

HRID 1949230Notes

Reaction equation

HRID 1949230 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[N:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([Cl:20])[CH:15]=3)[N:12]=[C:11]([C:21]([O:23]CC)=[O:22])[CH:10]=2)[CH:5]=[C:6]([F:8])[CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[N:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([Cl:20])[CH:15]=3)[N:12]=[C:11]([C:21]([OH:23])=[O:22])[CH:10]=2)[CH:5]=[C:6]([F:8])[CH:7]=1

Participants

3

Reactant 2

HCID 58277326HCID 58277326, compoundHCID 58277426HCID 58277426, compound

Product 1

HCID 58277390HCID 58277390, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 22A in analogy to the synthesis of the compound of Example 71A. 4.18 g (78% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-7dfb55e284304aeabb1784920e449f88
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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