HCID 58277326, compound → HCID 58277316, compound

HRID 1949232Notes

Reaction equation

HRID 1949232 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][C:17]([F:20])=[C:16]([Cl:21])[CH:15]=3)=[CH:12][C:11]([C:22]([O:24]CC)=[O:23])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8].ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][C:17]([F:20])=[C:16]([Cl:21])[CH:15]=3)=[CH:12][C:11]([C:22]([OH:24])=[O:23])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8]

Participants

3

Reactant 2

HCID 58277326HCID 58277326, compoundHCID 58277373HCID 58277373, compound

Product 1

HCID 58277316HCID 58277316, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 25A in analogy to the synthesis of the compound of Example 71A. 5.15 g (96% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-29b4b95d0c554397a5cf8c522894d36f
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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