HCID 58277326, compound → HCID 67153361, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([O:20][C:21]([F:24])([F:23])[F:22])[CH:15]=3)=[CH:12][C:11]([C:25]([O:27]CC)=[O:26])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8].ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([O:20][C:21]([F:23])([F:24])[F:22])[CH:15]=3)=[CH:12][C:11]([C:25]([OH:27])=[O:26])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8]Participants
3
Procedure
The preparation of the title compound takes place starting from the compound of Example 28A in analogy to the synthesis of the compound of Example 71A. 3.14 g (96% of theory) of the title compound are obtained.
Sources & evidence
- ORD record
- ord-fb492e8845a64c5ba7b3e956b9b945f8
- Source dataset
- uspto-grants-2013_03
- Patent number
- US08399682B2
Reaction notes
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