HCID 58277310, compound → HCID 58277288, compound
Reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([C:9]2[N:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([Cl:20])[CH:15]=3)[N:12]=[C:11]([C:21]([O:23]CC)=[O:22])[CH:10]=2)[CH:5]=[CH:6][C:7]=1[F:8].ClC1C=C(N2C(C3C=CC(F)=C(C(F)(F)F)C=3)=CC(C(O)=O)=N2)C=CC=1>>[Br:1][C:2]1[CH:3]=[C:4]([C:9]2[N:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([Cl:20])[CH:15]=3)[N:12]=[C:11]([C:21]([OH:23])=[O:22])[CH:10]=2)[CH:5]=[CH:6][C:7]=1[F:8]Participants
3
Procedure
The preparation of the title compound takes place starting from the compound of Example 34A in analogy to the synthesis of the compound of Example 77A. 3.30 g (98% of theory) of the title compound are obtained.
Sources & evidence
- ORD record
- ord-84cf0968efae47198ca746aca0f03795
- Source dataset
- uspto-grants-2013_03
- Patent number
- US08399682B2
Reaction notes
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