HCID 58277317, compound → HCID 58277407, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[C:17]([O:19][CH3:20])[CH:16]=[C:15]([F:21])[CH:14]=3)=[CH:11][C:10]([C:22]([O:24]CC)=[O:23])=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[C:17]([O:19][CH3:20])[CH:16]=[C:15]([F:21])[CH:14]=3)=[CH:11][C:10]([C:22]([OH:24])=[O:23])=[N:9]2)[CH:5]=[CH:6][CH:7]=1Participants
3
Procedure
The preparation of the title compound takes place starting from the compound of Example 41A in analogy to the synthesis of the compound of Example 71A. 1.31 g of the title compound are obtained.
Sources & evidence
- ORD record
- ord-2683f555e1a14472b3196f56472bda0f
- Source dataset
- uspto-grants-2013_03
- Patent number
- US08399682B2
Reaction notes
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