HCID 58277326, compound → HCID 58277392, compound

HRID 1949248Notes

Reaction equation

HRID 1949248 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[C:18]([O:20][CH3:21])[CH:17]=[C:16]([F:22])[CH:15]=3)=[CH:12][C:11]([C:23]([O:25]CC)=[O:24])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8].ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[C:18]([O:20][CH3:21])[CH:17]=[C:16]([F:22])[CH:15]=3)=[CH:12][C:11]([C:23]([OH:25])=[O:24])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8]

Participants

3

Reactant 2

HCID 58277326HCID 58277326, compoundHCID 58277458HCID 58277458, compound

Product 1

HCID 58277392HCID 58277392, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 42A in analogy to the synthesis of the compound of Example 71A but with stiffing for 6 hours. 1.38 g of the title compound are obtained.

Sources & evidence

ORD record
ord-ccc2bad0781b454e94a5b48d489fed5a
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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