HCID 58277305, compound → HCID 58277428, compound

HRID 1949249Notes

Reaction equation

HRID 1949249 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([C:20]#[N:21])[CH:15]=3)=[CH:12][C:11]([C:22]([O:24]CC)=[O:23])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8].ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([C:20]#[N:21])[CH:15]=3)=[CH:12][C:11]([C:22]([OH:24])=[O:23])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8]

Participants

3

Reactant 2

HCID 58277305HCID 58277305, compoundHCID 58277326HCID 58277326, compound

Product 1

HCID 58277428HCID 58277428, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 45A in analogy to the synthesis of the compound of Example 71A. 348 mg (68% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-8c6efd96d83a4569a6f20d4e3f724163
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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