HCID 58277326, compound → HCID 58277429, compound

HRID 1949251Notes

Reaction equation

HRID 1949251 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([C:20]([F:23])([F:22])[F:21])[CH:15]=3)=[CH:12][C:11]([C:24]([O:26]CC)=[O:25])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8].ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([C:20]([F:22])([F:23])[F:21])[CH:15]=3)=[CH:12][C:11]([C:24]([OH:26])=[O:25])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8]

Participants

3

Reactant 2

HCID 58277326HCID 58277326, compoundHCID 58277442HCID 58277442, compound

Product 1

HCID 58277429HCID 58277429, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 47A in analogy to the synthesis of the compound of Example 71A. 344 mg (97% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-c796b56a465946f1a6f930dc7dacb5b6
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

Loading…