HCID 58277326, compound → HCID 58277427, compound

HRID 1949252Notes

Reaction equation

HRID 1949252 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[C:18]([C:20]([F:23])([F:22])[F:21])[CH:17]=[C:16]([F:24])[CH:15]=3)=[CH:12][C:11]([C:25]([O:27]CC)=[O:26])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8].ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[C:18]([C:20]([F:22])([F:23])[F:21])[CH:17]=[C:16]([F:24])[CH:15]=3)=[CH:12][C:11]([C:25]([OH:27])=[O:26])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8]

Participants

3

Reactant 2

HCID 58277326HCID 58277326, compoundHCID 58277348HCID 58277348, compound

Product 1

HCID 58277427HCID 58277427, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 48A in analogy to the synthesis of the compound of Example 71A. 851 mg of the title compound with 51% purity are obtained.

Sources & evidence

ORD record
ord-04ba1d6470fc4cf0888bdc947795ac59
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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