HCID 58277326, compound → HCID 58277433, compound

HRID 1949256Notes

Reaction equation

HRID 1949256 reaction equation
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([C:15]2[N:19]([C:20]3[CH:25]=[CH:24][CH:23]=[C:22]([Cl:26])[CH:21]=3)[N:18]=[C:17]([C:27]([O:29]CC)=[O:28])[CH:16]=2)[CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([C:15]2[N:19]([C:20]3[CH:25]=[CH:24][CH:23]=[C:22]([Cl:26])[CH:21]=3)[N:18]=[C:17]([C:27]([OH:29])=[O:28])[CH:16]=2)[CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 58277326HCID 58277326, compoundHCID 58277355HCID 58277355, compound

Product 1

HCID 58277433HCID 58277433, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 43A in analogy to the synthesis of the compound of Example 71A. 60.0 g (85% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-7c3d877bdea54d65beb315b3237ece69
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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