HCID 58277326, compound → HCID 58277424, compound

HRID 1949258Notes

Reaction equation

HRID 1949258 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([O:20][CH3:21])[CH:15]=3)=[CH:12][C:11]([C:22]([O:24]CC)=[O:23])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8].ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([O:20][CH3:21])[CH:15]=3)=[CH:12][C:11]([C:22]([OH:24])=[O:23])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8]

Participants

3

Reactant 2

HCID 58277326HCID 58277326, compoundHCID 58277462HCID 58277462, compound

Product 1

HCID 58277424HCID 58277424, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 53A in analogy to the synthesis of the compound of Example 71A. 515 mg (93% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-b49f93aad88345b38ae72ce5e19db5c9
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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