HCID 58277359, compound → HCID 58277463, compound

HRID 1949259Notes

Reaction equation

HRID 1949259 reaction equation
[F:1][C:2]([F:31])([F:30])[C:3]1[CH:4]=[C:5]([C:13]2[N:17]([C:18]3[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[CH:19]=3)[N:16]=[C:15]([C:25]([O:27]CC)=[O:26])[CH:14]=2)[CH:6]=[C:7]([C:9]([F:12])([F:11])[F:10])[CH:8]=1.ClC1C=C(N2C(C3C=CC=CC=3F)=CC(C(O)=O)=N2)C=CC=1>>[F:30][C:2]([F:1])([F:31])[C:3]1[CH:4]=[C:5]([C:13]2[N:17]([C:18]3[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[CH:19]=3)[N:16]=[C:15]([C:25]([OH:27])=[O:26])[CH:14]=2)[CH:6]=[C:7]([C:9]([F:10])([F:11])[F:12])[CH:8]=1

Participants

3

Reactant 2

HCID 58277359HCID 58277359, compoundHCID 58277402HCID 58277402, compound

Product 1

HCID 58277463HCID 58277463, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 54A in analogy to the synthesis of the compound of Example 86A. 1.78 g (79% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-ab82eb42e4d74d099eb3a21af5505d3b
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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