HCID 58277297, compound → HCID 58277347, compound

HRID 1949262Notes

Reaction equation

HRID 1949262 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[C:18]([CH3:20])[CH:17]=[C:16]([F:21])[CH:15]=3)=[CH:12][C:11]([C:22]([O:24]CC)=[O:23])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8].ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[C:18]([CH3:20])[CH:17]=[C:16]([F:21])[CH:15]=3)=[CH:12][C:11]([C:22]([OH:24])=[O:23])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8]

Participants

3

Reactant 2

HCID 58277297HCID 58277297, compoundHCID 58277326HCID 58277326, compound

Product 1

HCID 58277347HCID 58277347, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 57A in analogy to the synthesis of the compound of Example 71A but with stiffing for 6 hours. 2.34 g of the title compound with 79% purity are obtained.

Sources & evidence

ORD record
ord-9fae5cde6b114f1dad9f217a123c6d7a
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

Loading…