HCID 58277303, compound → HCID 58277391, compound

HRID 1949263Notes

Reaction equation

HRID 1949263 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[C:17]([CH3:19])[CH:16]=[C:15]([F:20])[CH:14]=3)=[CH:11][C:10]([C:21]([O:23]CC)=[O:22])=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[C:17]([CH3:19])[CH:16]=[C:15]([F:20])[CH:14]=3)=[CH:11][C:10]([C:21]([OH:23])=[O:22])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 58277303HCID 58277303, compoundHCID 58277326HCID 58277326, compound

Product 1

HCID 58277391HCID 58277391, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 58A in analogy to the synthesis of the compound of Example 71A but with stiffing for 6 hours. 1.64 g (100% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-a086a41e93b44782bcd8fcdd5a306075
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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