HCID 58277326, compound → HCID 58277296, compound

HRID 1949267Notes

Reaction equation

HRID 1949267 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([C:20]#[N:21])[CH:15]=3)=[CH:12][C:11]([C:22]([O:24]CC)=[O:23])=[N:10]2)[CH:6]=[CH:7][CH:8]=1)#[N:2].ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[C:1]([C:3]1[CH:4]=[C:5]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([C:20]#[N:21])[CH:15]=3)=[CH:12][C:11]([C:22]([OH:24])=[O:23])=[N:10]2)[CH:6]=[CH:7][CH:8]=1)#[N:2]

Participants

3

Reactant 2

HCID 58277326HCID 58277326, compoundHCID 58277337HCID 58277337, compound

Product 1

HCID 58277296HCID 58277296, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 62A in analogy to the synthesis of the compound of Example 71A but with stiffing for 6 hours. 397 mg of the title compound with 36% purity are obtained.

Sources & evidence

ORD record
ord-366e46cd7d054d5ca82168652e13373c
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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