HCID 58277326, compound → HCID 58277398, compound

HRID 1949271Notes

Reaction equation

HRID 1949271 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH2:20][CH2:21][OH:22])[CH:14]=3)=[CH:11][C:10]([C:23]([O:25]CC)=[O:24])=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH2:20][CH2:21][OH:22])[CH:14]=3)=[CH:11][C:10]([C:23]([OH:25])=[O:24])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 58277326HCID 58277326, compoundHCID 58277361HCID 58277361, compound

Product 1

HCID 58277398HCID 58277398, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 66A in analogy to the synthesis of the compound of Example 71A. 11 mg (82% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-10da1c74026f4c8c9694436c934d2723
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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