HCID 58277284, compound → HCID 58277432, compound

HRID 1949274Notes

Reaction equation

HRID 1949274 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH2:20][CH2:21][CH2:22][N:23]4[CH2:27][CH2:26][CH2:25][CH2:24]4)[CH:14]=3)=[CH:11][C:10]([C:28]([O:30]CC)=[O:29])=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH2:20][CH2:21][CH2:22][N:23]4[CH2:27][CH2:26][CH2:25][CH2:24]4)[CH:14]=3)=[CH:11][C:10]([C:28]([OH:30])=[O:29])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 58277284HCID 58277284, compoundHCID 58277326HCID 58277326, compound

Product 1

HCID 58277432HCID 58277432, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 70A in analogy to the synthesis of the compound of Example 71A. 10 mg of the title compound with 79% purity (44% of theory) are obtained.

Sources & evidence

ORD record
ord-a16eeea18be4421da0bec554accf3a05
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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