1187917-12-9 → HCID 44230180, compound

HRID 1949280Notes

Reaction equation

HRID 1949280 reaction equation
ClC1C=C(C2N(C3C=CC=C(Cl)C=3)N=C(C(O)=O)C=2)C=C(F)C=1.[Cl:24][C:25]1[CH:26]=[C:27]([N:32]2[C:36]([C:37]3[CH:42]=[C:41]([F:43])[CH:40]=[C:39]([Cl:44])[CH:38]=3)=[CH:35][C:34]([C:45]([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=[O:46])=[N:33]2)[CH:28]=[CH:29][C:30]=1F>>[Cl:44][C:39]1[CH:38]=[C:37]([C:36]2[N:32]([C:27]3[CH:28]=[CH:29][CH:30]=[C:25]([Cl:24])[CH:26]=3)[N:33]=[C:34]([C:45]([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=[O:46])[CH:35]=2)[CH:42]=[C:41]([F:43])[CH:40]=1

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277390HCID 58277390, compound

Product 1

HCID 44230180HCID 44230180, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 72A in analogy to the synthesis of the compound of Example 1. 50 mg (84% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-6eca6c7a952847028d52a3a91234227b
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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