1187917-12-9 → HCID 44230125, compound

HRID 1949281Notes

Reaction equation

HRID 1949281 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[C:17]([F:19])[CH:16]=[C:15]([F:20])[CH:14]=3)=[CH:11][C:10]([C:21]([OH:23])=O)=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:14]=[C:15]([F:20])[CH:16]=[C:17]([F:19])[CH:18]=3)=[CH:11][C:10]([C:21]([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=[O:23])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277362HCID 58277362, compound

Product 1

HCID 44230125HCID 44230125, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 73A in analogy to the synthesis of the compound of Example 1. 28 mg (73% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-f921749075684c1b98b7c006933bc8eb
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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